Lance Armstrong
http://www.thedailyshow.com/video/index.jhtml?videoId=115112&title=lance-armstrong
At around 4:20, Jon Stewart asks him about the doping scandal, implying that he is obviously innocent. Lance's entire manner changes from relaxed and funny to nervous, serious and jerky. Interestingly, when he gets slightly emotional while talking about his illness (around 1:30), he is still much more like his normal self.
This is not a high-stake scenario. I typically don’t review low-stake lies:
http://eyesforlies.blogspot.com/2007/01/high-stake-lies.html
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bluebird commented
My strong suspicion is that he's a dope cheater but the question of just how widespread dope cheating is has always made me wonder. For example, some people say that the entire 100m line-up use illegal performance enhancing drugs, while other people say it's just 1 or 2.